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pCMV-VSV-G 載體序列

發(fā)布時(shí)間:2013/8/7      點(diǎn)擊次數(shù):1821

 pCMV-VSV-G 載體序列

型號(hào) 載體名稱 出品公司 載體用途
VMA0369 pCMV-VSV-G Addgene 慢病毒載體

產(chǎn)品參數(shù): 

5' sequencing primer: T7

載體抗性: 
氨芐青霉素(Ampicillin)
載體描述: 

Vector for constitutive expression of VSV-G glycoprotein. Also known as pHCMV-G or pHCMV-VSV-G.

Retroviruses are efficient tools for delivering heritable genes into the genome of dividing cells. pCMV-VSV-G expresses the G glycoprotein of the vesicular stomatitis virus (VSV-G) under the control of the CMV immediate-early promoter. VSV-G is used in pseudotyping of Moloney Murine Leukenia Virus(MMLV)-based retroviral vectors by mediating viral entry. VSV-G interacts with phospholipidcomponents of the target cell membrane and fosters the fusion of viral and cellular membranes. VSV-G does not require a cell surface receptor and can serve as a surrogate viral envelope protein. 
The vector contains the ampicillin-resistance gene for propagation and antibiotic selection in bacteria.

質(zhì)粒圖譜: 
pCMV-VSV-G 質(zhì)粒圖譜
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