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Apolipoprotein(阿樸脂蛋白)-H(β2GP-1)說明書

發(fā)布時(shí)間:2013/7/12      點(diǎn)擊次數(shù):2549

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Enzyme Research 是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年Enzyme Research Laboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。Enzyme Research通過不斷追求產(chǎn)品的zui高品質(zhì),贏得了世界各地凝血研究實(shí)驗(yàn)室的信任。
Enzyme Research Laboratories為生物技術(shù)公司,制藥行業(yè)、醫(yī)院和大學(xué)的研究實(shí)驗(yàn)室提供用于的純化抗凝因子。除了其制造能力,Enzyme Research Laboratories也創(chuàng)新研發(fā)領(lǐng)域中的血液凝固技術(shù)。

Apolipoprotein-H(β2GP-1)

 

HAPO-H          Apolipoprotein-H(β2GP-1)

Apolipoprotein-H, also known as β2Glycoprotein-1 (β2GP-1) is a plasma glycoprotein that circulates at a concentration of 200 µg/mL (4mM). β2GP-1 has been identified as a constituent of chylomicrons, very low density lipoproteins and high density lipoproteins in Human plasma. It has also been demonstrated to bind phospholipids, heparin and plaets where it can modulate the activity of adenylate (19%). Although the precise function(s) are as yet unknown, β2GP-1 has been shown to interfere with blood coagulation by competitively binding to phospholipids exposed during cell activation or damage. Recent evidence also implicates β2GP-1 as a cofactor recognized by some anti-phospholipid antibodies present in autoimmune disorders such as systemic lupus erythematosus(SLE).

Buffer composition = 20 mM Tris-HCl/0.3 M NaCl /pH 7.3
Extinction Coefficient (1%) = 9.4
Molecular Weight = 48,000 daltons

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